Phosphocreatine-dependent protein phosphorylation in rat skeletal muscle
نویسندگان
چکیده
منابع مشابه
Interpreting the phosphocreatine time constant in aerobically exercising skeletal muscle.
TO THE EDITOR: Francescato et al. (1) contrast the lack of interindividual correlation between the phosphocreatine (PCr) time constant ( PCr) and the ADP concentration ([ADP]) change from rest to steady state ( [ADP]S) during moderate aerobic exercise with the fact that “. . .ADP concentration is commonly thought to be one of the main feedback signals controlling mitochondrial respiration” (1),...
متن کاملMeasuring energy diffusion: phosphocreatine in human skeletal muscle.
Introduction The creatine kinase (CK) reaction plays a central role in energy transfer in the myocyte, shuttling high-energy phosphate (HEP) created in the mitochondria, to sites of utilization in the myofibrils [1,2]. At the mitochondria, the reverse reaction produces phosphocreatine (PCr) from adenosine triphosphate (ATP) and creatine (Cr). PCr diffuses to the myofibrils to regenerate ATP fro...
متن کاملSkeletal muscle phosphocreatine recovery in exercise-trained humans is dependent on O2 availability.
In skeletal muscle, phosphocreatine (PCr) recovery from submaximal exercise has become a reliable and accepted measure of muscle oxidative capacity. During exercise, O2 availability plays a role in determining maximal oxidative metabolism, but the relationship between O2 availability and oxidative metabolism measured by 31P-magnetic resonance spectroscopy (MRS) during recovery from exercise has...
متن کاملSkeletal muscle phosphocreatine depletion depresses myocellular energy status during sepsis.
OBJECTIVE To determine the effects of phosphocreatine (PCr) depletion on myocellular energetics. DESIGN Randomized controlled study. SETTING University laboratory. MATERIALS Thirty-eight adult male Wistar rats (110-121 g). METHODS The poorly metabolized creatine analogue beta-guanidinopropionic acid, (beta-GPA, 2% of a gel diet) was fed to the rats for 14 days to replace (75%) endogenou...
متن کاملEffect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis.
Biopsy samples were obtained from the vastus lateralis muscle of eight subjects after 0, 20, 60, and 120 s of recovery from intense electrically evoked isometric contraction. Later (10 days), the same procedures were performed using the other leg, but subjects ingested 20 g creatine (Cr)/day for the preceding 5 days. Muscle ATP, phosphocreatine (PCr), free Cr, and lactate concentrations were me...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1992
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2840115